UPDATE 10:18 P.M.:

All lanes of traffic are now open on the H-1 Eastbound by the Kaahumanu Overpass.

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Three most right lanes of the H-1 Eastbound are closed by the Kaahumanu Overpass due to an on-going police investigation. 

At least one person is confirmed dead at the scene. 

Two most left lanes are currently still open for travel.  Drivers advised to expect delays and use alternative routes.