The dead mice will target snakes in a fenced-in area of the base, he said, so officials will be able to determine the effectiveness in that area versus an adjacent area that the snakes could move in and out of.
"We have a site where there's a population of snakes that nobody can get into. It's a controlled population," Vice told the Pacific News Center. "This is being done in a very rigorous, scientific manner. This isn't just something that we've just kind of come up with by the seat of our pants."
And if the test works, more snakes could be confronting death from above.
"We want to make sure we are doing it right. If the information shows that it's effective in controlling the population, we will institute a plan to use it across areas in Guam," Vice told the Pacific Daily News.