Honolulu police say Kamehameha Highway was closed in both directions near Ka'a'awa Place due to a vehicle crash. They say fluids on the road need to be cleaned up.
The announcement was made just after 11:30 a.m.
The apparent head-on collision happened at around 10:30 a.m., according to Emergency Medical Services officials.
A 38-year-old woman was taken to the hospital in serious condition.
The road was reopened by 1:30 p.m.
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